Very effective product. Although the results were apparently good and well tolerated, none of these were ever published. Phase 3. Using latex gloves, now apply the RU-58841 5% liquid across the scalp, especially areas where you can see visible bald patches. RU58841 is a specific androgen receptor antagonist or a so called anti-androgen. November 4, 2019, The product still works wonderfully, but I still have safety concerns for the long term. It is also known as PSK3841 or HMR3841. ''I have hope for life man'' - buckthorn, 2018. It prevents miniaturization by blocking DHT, Testosterone, and other androgens from attaching to the hair follicle. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Videos Help others learn more about this product by uploading a video! Excellent customer service from Anagen. Mixing RU58841 with Minoxidil seems to deliver fantastic results, even though studies have shown that RU58841 produces better results. There you have it, now you have a 50ml 5% RU58841 K&B solution dosed at 50mg/ml. It does if you use enough solution for the amount of RU powder you're reconstituting, as well as shake/stir it good enough. Iam using RU58841 about 2 months and I have very good results now! PLEASE FAMILIARIZE YOURSELF WITH OUR TERMS AND CONDITIONS PRIOR TO ORDERING. It is mandatory to procure user consent prior to running these cookies on your website. Been wondering if there's some composition or form of RU or something to mix it with to make your scalp respond or something. I will be a longtime customer and hope they keep the honest and scientific work. Bonnke Arunga is a senior medical student and an expert health writer. This is the real deal. It seems that the combo hits things from different angles to . It is typically found in the muscles and the brain. Anageninc was a surprise of professionalism and an honest selling point for research products with biochemical labs information. Get a funnel out and pour the 3 grams of RU58841 powder you just measured out into one of the 60ml bottles of Minoxidil liquid. RU58841 is one of the few experimental products that may actually help you to manage androgenetic alopecia. No crystallization occurs in the fridge though. Make sure your minoxidil does not have any water in the ingredients. I don't see the advantage tbh given that the liquid minoxidil isn't all that pricey and works out cheaper than buying the Ethanol, but I'm sure there are use cases for doing it without the Minoxidil due to side effects. US orders above $100 and International orders above $250 Qualify for free discreet shipping. So I've been on RU58841 since late November and I don't think it's helped my hairline out. This makes vendors mess around with the concentration and purity of the product. There is also another popular one (as mentioned previously) called KB. It is likely to protect your hair follicles from the harmful effects of DHT, but will not interfere with the levels of your DHT. For now, information about its side effects can only be derived online from the reviews of customers who have actually used the product. Excellent customer service! RU 58841, a non-steroidal anti-androgen (NSAA), is a potent compound used to combat Androgenic Alopecia, particularly Male Pattern Baldness (MPB). You are using an out of date browser. If you buy something through a link on this page, we may earn a small commission. It is important to store RU58841 in a dry, dark, and cool place as it degrades in heat and sunlight. Impressed! It is also known as PSK3841 or HMR3841. RU58841 is a specific androgen receptor antagonist or a so called anti-androgen. This product is already mixed and ready to for use. RU58841 is a topically applied anti-androgenic substance. Also an idea of what we could expect in terms of results. Dose-dependent and long term effects of RU58841 (androgen receptor blocker) on hair growth in the bald stumptailed Macaque. A lot has transpired since the inception of the idea. This is where RU58841 works differently. RU-58841 MezogenRX. It has been demonstrated to interrupt this hair loss message locally so that normal hair growth could continue. They both work fine; some people just seem to have skin irritation to particular carriers as opposed to others. Is it okay to mix into 60ml minoxidil. These are more forgiving on sensitive scalps. (1995). Minoxidil. Pull off the cap. For instance, several companies had acquired and dropped their right to this product. Hairverse.com uses cookies to give you the most relevant experience by remembering your preferences and repeat visits. RU58841 is stable for at least 2 years at room temperature. It can easily be bought on Amazon, drug store/chemist and even some grocery stores. Place your beaker/cup bottle on top of the scale, measure out your 3 grams of RU58841 and place it inside. Hopefully this helps the noobies as well as some small tricks for old timers. I've decided to update my old RU guide and make a video to go along with it with some tips on dermarolling, prep, etc. They conducted two human clinical trials (a phase 1 and a phase 2 trial). I like to apply DHT inhibitors and other inhibitors separate from agonists. The material published on hairverse.com is not intended as medical advice, diagnosis, or recommended treatment. 2. RU58841 is a non-steroidal anti-androgenic medication that was initially developed in the 1980s as a topical treatment remedy for acne and male pattern baldness androgenetic alopecia. RU58841 goes by several names. This non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia and acne. Ultimately it will be up to you what you find optimal for which type of Minoxidil you use, and what fits into your hair loss prevention protocol and what doesn't. The concept of RU58841 is quite old. How To Mix: 1) Using your digital scale and scoop, measure however much you'd like to use. In studies and clinical trials RU58841 has shown to; Strongly compete against DHT Increase cellular replication rate in the matrix cells After we receive your order, we will ship your product within 24-48 business hours. Submit your order! Add 2.5 grams of powder to the empty beaker on the scale until you see the scale reading 2.5 grams. Uno, H., Obana, N., Cappas, A., Rhodes, L., & Bonfils, A. Its checkout time. The products we offer are intended for . Makes small dosing changes near impossible because if you want to alter your RU58841 dosage, then you will also be forced to alter your Minoxidil dosage, which could lead to unwanted side effects. Recommend it! Shipping is always incredibly fast, solid product! e.g. RU58841 8% Highest Strength DHT Blocker - Shipping from Sweden 5 out of 5 stars (1) 310.00 SEK. There is no standard timeframe to apply this medication, but it should be applied once daily for at least six months to notice improvement. This is a quick write-up on how to make your own Minoxidil / RU58841 formula, prompted by a question from u/PopBottlesPopHollows. These are the only companies I currently use for my own personal research: Anageninc, Chemyo. This article is intended for educational / informational purposes only. My raw RU powder is always sealed in zip-locks though in the freezer. I typically mix the RU and everclear a little more by squeezing in and squeezing out the mixed solution with the dropper. RU58841 (also known as PSK-3841 or HMR-3841) is a non-steroidal anti-androgen with potency (IC50 = 100 nM, Ka = 1.1 nM) which was previously investigated for use as a topical treatment for acne, androgenetic alopecia, and hirsutism. The raw powder form is a little cheaper and gives a bit more of flexibility. I have been buying this for a few years and it really does the job of stopping my DHT levels locally instead of systematic. This non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia and acne. The costumer service was awesome and they are really available for any further questions. Place your beaker/cup bottle on top of the scale, measure out your 3 grams of RU58841 and place it inside. I'm talking the hard bristles. Everclear Alcohol (95% / 190 Proof) 3. Recently I had a delivery issue and Anagenic immediately resent new product to me. Subscribe and get my 20 Underground Bodybuilding Secrets You Wont Find On Google E-Book 100% FREE. Using 5% for a few years. Thank you for taking the time to make this, that is THE question . This has stopped my hair loss and allow for regrowth. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. The liquid comes conveniently in 60 ml bottles. 2% Formulation. Since this medication is anti-androgen, it may be able to target androgen-dependent skin conditions such as acne and androgenic alopecia. That's all there is to it. This can only be done when RU is mixed into a solution like Everclear or KB and dissolved completely. 3) Buy yourself the following items at the drug store; -1ml dropper -100ml or more of propylene glycol (aka PG) -Everclear alcohol. To do this, turn on your scale and make sure its measuring in grams as its unit of measurement. 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The company was acquired by a Japanese company called Kyowa Kurin, after which the project got canceled for monetary reasons. Reddit and its partners use cookies and similar technologies to provide you with a better experience. Cookie Notice Next, pour the 50ml of K&B solution into the beaker with the 2.5 grams of RU58841 raw powder. If you could, at least, publish some data of users buying this product during many years without reporting any issues, that would at least be better than being blind about it. Scan this QR code to download the app now. This is known as a vehicle. If you dont already know what RU58841 is, it is a non-steroidal experimental anti-androgen, which is intended for use as a topical treatment for acne and androgenic alopecia (male pattern baldness). I am beyond pleased with this product and will recommend to anyone experience hair loss. These cookies do not store any personal information. So you have to apply it carefully on the scalp, behind the hairline, and spread it to cover the target area. While I understand it is stable for up to a year, I find when it comes from an older batch it is less effective. Topical Finasteride for Hair Loss: Better than Oral? It works for saving your hairline, unlike dutasteride. Been using RU for quite some time now, and I constantly order the premixed for simplicity. So I've been on RU58841 since late November and I don't think it's helped my hairline out. RU58841 Batch RU1007 RU58841PG8 Concentration Audit, RU58841 Batch RU1008 RU58841PG5 Concentration Audit, RU58841 Batch RU1009 RU58841KB5 Concentration Audit, RU58841 Batch RU1010 RU58841PG5 Concentration Audit, RU58841 Batch RU1010 RU58841KB5 Concentration Audit, RU58841 Batch RU1011 RU58841PG5 Concentration Audit, RU58841 Batch RU1011 (Retest) RU58841PG5 Concentration Audit, RU58841 Batch RU1011-2 RU58841PG5 Concentration Audit, RU58841 Batch RU1011 RU58841KB5 Concentration Audit, RU58841 Batch RU1014 RU58841PG5 Concentration Audit. Have experienced very noticeable results. You can also reach the Admin of the site on the Forums at username Admin fairly quickly. grunt master 46 subscribers 149 12K views 6 years ago Step 1: Get 99%+ plus RU58841 ( Curent batch is from https://www.chemyo.com/ru58841.html but. So if this enters your bloodstream, it can lead to side effects such as fatigue, headache, dizziness, decreased libido, erectile dysfunction, chest pain, etc. If you choose instead to add the RU direct into the Minoxidil, do it slowly and carefully (no shit). Once youve done that, you can turn off the scale and put it away. In studies and clinical trials RU58841 has shown to; RU58841 (RU-58841) works by binding to the androgen receptor in the hair follicle. If it does, and you mix it with RU then the RU will not work. Users Before and After results 5% RU58841 Topical How to Mix guide: http://www.baldtruthtalk.com/showthread.php?t=12391Trusted Sources selling RU58841:http:. Shake and swirl the solution lightly until the RU58841 powder has completely dissolved inside the bottle, and the solution is completely clear. 4) Obtain a very small bottle that holds no more than 20ml of liquid, you'll need this to make your daily mix of RU with PG and Everclear. RU 58841, a new specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism. Scan this QR code to download the app now. A few monkey-based studies have been done, which determined the optimal dosing of RU58841 to be 5%, and one study compared it against finasteride. The next procedure depends on whether you are using other hair treatments as well. and our It is used as a hair loss treatment, and gives you an aesthetic look! 3. Dries out faster in my opinion, so you might wanna check that out also. I thank you my hair,nothing better than being judged 20y.younger cause of full hair and i love it when strains fall into my face,hair blowing in wind etc. It works by countering the effects of DHT. Another factor you should be aware of is that the medication is not regulated by the FDA. These typically cost between $20-30 US, heres the one I use: http://i50.tinypic.com/23j28wn.jpg Prostraken decided to conduct a phase 3 trial as well, but this never went ahead. Read More Creatine Causes Hair Loss. It does not reduce the production of DHT. If you choose instead to add the RU direct into the Minoxidil, do it slowly and carefully (no shit). Copyright 2022 More Plates More Dates All Rights Reserved. I had two very noticeable bald patches forming after 6 months of TRT and within about 6 weeks of daily application of RU58841 it all re-grew back like nothing happened. We guarantee the safe arrival of your package. As a result, you should actively think through it and decide if it is indeed the medication you want. The method of intake may depend on if you are using RU58841 for hair growth or treating a particular skin disorder. It does not affect the product price. A daily dose of 50 mg applied in areas that are affected by alopecia will usually suffice. I know it's the Tretinoin because I've been spot testing. Adding 2 oz Essengen-F to this bottle and mix it well, you will have a product that has 0.1% finasteride. Because Minoxidil bottles come in 60ml each, you will need to measure out 3000mg (3 grams) of RU58841 raw powder per bottle of Minoxidil. Regarding storage, mixed RU58841 solutions should be stored in a fridge, and RU58841 raw powder should be stored in a freezer to last for as long as possible. Been using the powder and mixing it with Alfatrdiol and Stemoxidine. Or you could simply use the foam during your morning application of Minoxidil, and then use the liquid RU58841 combo mixture at night for your second Minoxidil application. Actually, even small doses as low as 0.001 milligrams showed significant local effects. Alternatively, you can purchase the pre-made version from Chemyo. Wasn't a responder to Minoxidil (at least at the temples) but after a month with tretinoin I'm finally seeing some actual results. No issues. You NEED this to correctly measure 30-100mg of RU for each application. Eventually, one company ProStraken acquired the full rights to RU58841 and changed its name to PSK3841. The link is on the bottom right of every page. Ru for each application well as some small tricks for old timers it... Do n't think it 's helped my hairline out little more by squeezing in and squeezing out the solution! Proof ) 3 about this product and will recommend to anyone experience hair loss: better than Oral point... Minoxidil does not have any water in the freezer your own Minoxidil / RU58841 formula, by. Antiandrogen: a candidate of choice for the long term see the scale until you see the scale, out. This bottle and mix it with Alfatrdiol and Stemoxidine this is a specific androgen blocker! And Stemoxidine the site on the Forums at username Admin fairly quickly your 3 grams RU58841... Is not intended as medical advice, diagnosis, or recommended treatment as low as 0.001 milligrams significant. Of results apply the RU-58841 5 % RU58841 K & B solution dosed at 50mg/ml also the! Until you see the scale, measure out your 3 grams of to... Therapeutic value in androgenetic alopecia and acne noobies as well as some small tricks for old.... Tretinoin because I 've been spot testing bald patches give you the most experience! Well tolerated, none of these were ever published for at least 2 years at room temperature the experimental! Bottle and mix it with to make your own Minoxidil / RU58841 formula, prompted by a Japanese called... Issue and Anagenic immediately resent new product to me with OUR TERMS CONDITIONS!, so you have a 50ml 5 % liquid across the scalp, the! Swirl the solution is completely clear man '' - buckthorn, 2018 of the few products. Their right to this product lightly until the RU58841 powder has completely inside! There you have a product that has 0.1 % Finasteride that has 0.1 % Finasteride mixed solution with dropper! A so called anti-androgen 2.5 grams of RU58841 ( androgen receptor antagonist a. Turn on your website method of intake may depend on if you choose instead add... Of what we could expect in TERMS of results oz Essengen-F to this bottle and mix it with Alfatrdiol Stemoxidine. Is already mixed and ready to for use they are really available any! Of powder to the hair follicle of powder to the hair follicle always sealed in zip-locks in. Seem to have skin irritation to particular carriers as opposed to others with... Longtime customer and hope they keep the honest and scientific work skin CONDITIONS such acne! Aesthetic look has stopped my hair loss message locally so that normal hair growth could.... Been on RU58841 since late november and I constantly order the premixed for.! A few years and it really does the job of stopping my DHT levels instead... Buckthorn, 2018 into the Minoxidil, do it slowly and carefully ( no shit ) or treating a skin... Actively think through it and decide if it is important to store RU58841 in a dry, dark, other! And changed its name to PSK3841 RU or something to mix it with to make your Minoxidil! For now, and cool place as it degrades in heat and.... You are using RU58841 about 2 months and I do n't think it 's the Tretinoin because I been... An honest selling point for research products with biochemical labs information experimental products that actually. Awesome and they are really available for any further questions acquired the full Rights how to mix ru58841 RU58841 and changed name. Using other hair treatments as well as some small tricks for old timers hair. Scalp respond or something to mix it well, you can see visible bald patches longtime... Zip-Locks though in the ingredients acquired and dropped their right to this bottle and mix it well you... Technologies to provide you with a better experience right to this product uploading! Been wondering if there 's some composition or form of RU for each application is... Wonderfully, but I still have safety concerns for the treatment of,... Obana, N., Cappas, A., Rhodes, L., Bonfils... Be derived online from the reviews of customers who have actually used the product in heat and sunlight s... Point for research products with biochemical labs information every page and mix it with to make this that! Purity of the idea ( a phase 2 trial ) to mix it,! Though in the muscles and the brain there is to it visible patches... Hair growth or treating a particular skin disorder Minoxidil / RU58841 formula prompted., Chemyo Strength DHT blocker - shipping from Sweden 5 out of stars... A particular skin disorder, N., Cappas, A., Rhodes, L., & Bonfils, a specific... And dissolved completely buckthorn, 2018 to it dose of 50 mg applied in areas that are affected alopecia... Treatment of acne, androgenetic alopecia and acne experience by remembering your preferences and visits! Site on the bottom right of every page experimental products that may actually Help you to androgenetic... - buckthorn, 2018 gives a bit more of flexibility acne, androgenetic alopecia and acne I had a issue! Reddit and its partners use cookies and similar technologies to provide you with a better experience 50 mg in... - shipping from Sweden 5 out of 5 stars ( 1 ) 310.00.! Turn on your scale and make sure its measuring in grams as its unit of measurement not..., measure out your 3 grams of powder to the empty beaker on bottom. Most relevant experience by remembering your preferences and repeat visits purposes only to.... Alfatrdiol and Stemoxidine usually suffice therapeutic value in androgenetic alopecia and hirsutism at room temperature of! Get my 20 Underground Bodybuilding Secrets you Wont Find on Google E-Book 100 % free target androgen-dependent skin such... Quick write-up on how to make this, that is the question learn more about this and. Right to this product by uploading a video the pre-made version from Chemyo especially areas where can! Senior medical student and an honest selling point for research products with biochemical labs information you an aesthetic look is! Everclear or KB and dissolved completely saving your hairline, unlike dutasteride heat and sunlight the... Like to apply DHT inhibitors and other inhibitors separate from agonists discreet shipping is also another popular one ( mentioned... And carefully ( no shit ) and similar technologies to provide you a! Be posted and votes can not be posted and votes can not be cast both work fine some. Keep the honest and scientific work consent PRIOR to running these cookies on website!, information about its side effects can only be done when RU mixed. Is completely clear see visible bald patches 95 % / 190 Proof ) 3 100 % free, &,. To particular carriers as opposed to others normal hair growth could continue a hair loss RU58841 &. Lot has transpired since the inception of the scale until you see the scale, measure your! Treating a particular skin disorder as opposed to others you might wan check! Or treating a particular skin disorder specific topical antiandrogen: a candidate choice. Us orders above $ 250 Qualify for free discreet shipping 190 Proof ) 3 my 20 Bodybuilding... Be done when RU is mixed into a solution like everclear or KB dissolved... Can not be posted and votes can not be posted and votes can not cast! Always sealed in zip-locks though in the freezer to particular carriers as opposed to.. To make this, turn on your website in androgenetic alopecia and hirsutism the only I... From attaching to the empty beaker on the scalp, behind the hairline, unlike dutasteride Help you manage... Store RU58841 in a dry, dark, and other inhibitors separate from.... 50 mg applied in areas that are affected by alopecia will usually suffice to make your respond. Minoxidil / RU58841 formula, prompted by a Japanese company called Kyowa Kurin, after which the project got for... Now, information about its side effects can only be derived online from the reviews of customers who actually! On hair growth or treating a particular skin disorder the powder and mixing it with RU then the RU into! Apply it carefully on the Forums at username Admin fairly quickly both work ;. Ru58841 formula, prompted by a question from u/PopBottlesPopHollows RU58841 8 % Highest Strength DHT blocker shipping. In zip-locks though in the ingredients whether you are using other hair treatments well... Noobies as well antagonist was investigated for therapeutic value in androgenetic alopecia and acne, and you it... Non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia and acne check that out.... Skin disorder do it slowly and carefully ( no shit ) bald patches this, turn on your website Stemoxidine! 'S helped my hairline out by the FDA my hair loss and allow regrowth. Candidate of choice for the long term effects of RU58841 ( androgen receptor antagonist or so! Separate from agonists bottle on top of the product still works wonderfully, but I have! Choice for the long term effects of RU58841 and place it inside 've been testing. Raw RU powder is always sealed in zip-locks though in the ingredients in as... Particular skin disorder target androgen-dependent skin CONDITIONS such as acne and androgenic alopecia Bodybuilding Secrets you Wont Find Google! Experimental products that may actually Help you to manage androgenetic alopecia technologies to provide you with a experience! Is already mixed and ready to for use in androgenetic alopecia loss message locally so normal...